INTERNATIONAL BURCH UNIVERSITY
Graduate Study - Faculty of Engineering and Natural Sciences
Genetics and Bioengineering PhD
2013-2014

SYLLABUS
Code Name Level Year Semester
GBE 622 Advanced Topics in Forensic DNA Analysis Graduate 1 Spring
Status Number of ECTS Credits Class Hours Per Week Total Hours Per Semester Language
7.5 127 English

Instructor Assistant Coordinator
, Damir Marjanović, Prof. Dr.
no email no email

COURSE OBJECTIVE
Students will get to know the newest methods of DNA analysis in Forensic genetics. Paternity testing, identification of crime perpetrators or missing individuals will be shown through real cases. During the presentations attendants will be introduced with basic information about DNA forensic laboratory practice (DNA isolation from various samples, polymerase chain reaction, gel electrophoresis, capillary electrophoresis and analyses harvested results), usage of genetic markers within forensic genetics, forensic DNA data-basing, court testimony, challenges within presentation of the forensic DNA analysis results on the court etc.

COURSE CONTENT
Week
Topic
  1. Basic Genetics and Human Genetic Variation.
  2. Forensic DNA Analysis and Statistics.
  3. Forensic Aspects of mtDNA Analysis.
  4. Y Chromosome in Forensic Science.
  5. Forensic Application of X Chromosome STR s and SNPs.
  6. Low Copy Number DNA Profiling. Forensic DNA Mixtures, Approaches, and Analysis.
  7. Forensic DNA Typing and Quality Assurance. Collection and Preservation of Physical Evidence.
  8. Midterm Examination.
  9. Identification by DNA and Identification of Missing Persons and Mass Disaster Victim.
  10. Forensic Animal DNA Analysis. Application of DNA- Based Methods in Forensic Entomology.
  11. Forensic Tissue Identification with Nucleic Acids. Evolving Technologies in Forensic DNA Analysis.
  12. Prediction of Physical Characteristics, such as Eye, Hair and Skin Color Based Solely on DNA.
  13. DNA as Evidence in the Courtroom. Some Ethical Issues in Forensic Genetics.
  14. Final Examination.

LABORATORY/PRACTICE PLAN
Week
Topic

    TEACHING/ASSESSMENT
    Description
    • Lectures
    • Presentation
    • Seminar
    • Project
    • Case Studies
    • Demonstration
    Description (%)
    Method Quantity Percentage (%)
    Homework110
    Project120
    Midterm Exam(s)120
    Presentation110
    Final Exam140
    Total: 100
    Learning outcomes
    • Usage all sorts of forensic and genetic analysis methods in processing human, animal and plant biological trace samples.
    • Collecting forensic samples for DNA analysis.
    • Getting experience in all sorts of theoretical knowledge in forensic science based on newest methods of DNA technology and its usage in legal medicine and juridical procedures.
    • Identification based on low-copy DNA samples commonly used for identification of crime perpetrators, mass disaster casualties and paternity testing and understanding techniques currently used in forensic genetics including short tandem repeats (STR) analysis and interpretation, population genetics and mitochondrial and Y chromosome markers.
    • Understanding basic techniques important for creating and usage of National DNA data base and understanding basic biostatistical principles in forensic genetics and introduction of the newest molecular biology techniques used in forensic sciences - understanding of problems in applied forensic genetics and studying reference literature of this field.
    TEXTBOOK(S)
    • Butler JM. Forensic DNK Typing: Methodology, Technology and Genetics of STR Markers (2nd edition). London: Elsevier Academic Press; 2012.

    ECTS (Allocated based on student) WORKLOAD
    Activities Quantity Duration (Hour) Total Work Load
    Lecture (14 weeks x Lecture hours per week)16580
    Laboratory / Practice (14 weeks x Laboratory/Practice hours per week)16232
    Midterm Examination (1 week)155
    Final Examination(1 week)11010
    Preparation for Midterm Examination 0
    Preparation for Final Examination7.50
    Total Workload: 127
    ECTS Credit (Total workload/25): 5