INTERNATIONAL BURCH UNIVERSITY
Graduate Study - Faculty of Engineering and Natural Sciences
PhD Genetics and Bioengineering
2014-2015

SYLLABUS
Code Name Level Year Semester
GBE 614 Antimicrobial Resistance Graduate 1 Fall
Status Number of ECTS Credits Class Hours Per Week Total Hours Per Semester Language
6 150 English

Instructor Assistant Coordinator
Mirsada Hukić, Prof. Dr. Mirsada Hukić, Prof. Dr.
[email protected] no email

Introduction to molecular principles of antimicrobial resistance, communications between microorganisms and their environmental; trends in the control of antimicrobial resistance and surveillance.

COURSE OBJECTIVE
Describe the biological mechanisms of antibiotic resistance.
Critically evaluate the design and results of epidemiologic studies that report risk factors and prevention measures for antibiotic resistance.
Understand the interaction between individual treated patients and the population in the spread of antibiotic resistance.
Introduction to molecular principles of antimicrobial resistance, communications between microorganisms and their environmental; trends in the control of antimicrobial resistance and surveillance.

COURSE CONTENT
Week
Topic
  1. Antimicrobial resistance as a global risk and serious threat
  2. Introduction to antimicrobial resistance
  3. Antibiotics
  4. Environmental impact
  5. Mechanisms of antimicrobial resistance
  6. Multidrug-resistant pathogens (MDR) and extensively drug-resistant pathogens (XDR)
  7. Resistant pathogens: bacteria, viruses, fungi
  8. Quorum sensing in bacterial virulence
  9. Quorum sensing in biofilm formation
  10. Quorum sensing in communication between bacteria and human cells
  11. Quorum quenching in agents
  12. Antimicrobial resistance testing - Microbiology Laboratory
  13. Surveillance of antimicrobial resistance
  14. Antimicrobial resistance and infection control

LABORATORY/PRACTICE PLAN
Week
Topic

    TEACHING/ASSESSMENT
    Description
    • Presentation
    • Project
    • Assignments
    • Other:In-group discussion
    Description (%)
    Method Quantity Percentage (%)
    Project20
    Midterm Exam(s)120
    +In-group discussion20%
    Total: 40
    Learning outcomes
    • Working knowledge of antimicrobial resistance threat
    • Understanding of procedures and methods
    • Focus on public health preparedness, surveillance systems and international networks
    TEXTBOOK(S)
    • Microbiology 7th Ed. (2008) Prescott, Harley and Klein
    • Numanović F, Hukić M, Aščerić M, Delibegović Z, Nurkić J. Medicinska mikrobiologija sa imunologijom i parazitologijom. Tuzla: OFF-SET Tuzla, 2014
    • http://www.who.int/drugresistance/en/
    • http://www.cdc.gov/drugresistance/
    • http://www.ecdc.europa.eu/en/healthtopics/antimicrobial_resistance/pages/index.aspx

    ECTS (Allocated based on student) WORKLOAD
    Activities Quantity Duration (Hour) Total Work Load
    Lecture (14 weeks x Lecture hours per week)14342
    Laboratory / Practice (14 weeks x Laboratory/Practice hours per week)14228
    Midterm Examination (1 week)122
    Final Examination(1 week)133
    Preparation for Midterm Examination11010
    Preparation for Final Examination11515
    Assignment / Homework/ Project12525
    Seminar / Presentation12525
    Total Workload: 150
    ECTS Credit (Total workload/25): 6