INTERNATIONAL BURCH UNIVERSITY
Faculty of Engineering and Natural Sciences
Department of Genetics and Bioengineering
2017-2018

SYLLABUS
Code Name Level Year Semester
GBE 338 Immunology and Immunogenetics Undergraduate 3 Spring
Status Number of ECTS Credits Class Hours Per Week Total Hours Per Semester Language
Area Elective 5 2 + 2 125 English

Instructor Assistant Coordinator
Monia Avdić - Ibrišimović, Assist. Prof. Dr. Monia Avdić Monia Avdić - Ibrišimović, Assist. Prof. Dr.
[email protected] [email protected] no email

This course provides a broad survey of modern immunology, covering such topics as molecular concepts of antigenic specificity, chemistry of antibodies and their interactions with antigens and cells, regulation of the immune response etc. The basic immune system organs will be analyzed as well blood, hemopoesis and the genetics of blood groups. The course is taken concurrently with a lab course, which is teaching students basic experimental concepts in immunology, such as differential blood picture, counting blood cells, ELISA testing, and hemoglobin analysis.

COURSE OBJECTIVE
The cognitive, affective and behavioral objectives of this course are following:
1. Providing a theoretical and applied perspective of classical and modern immunology.
2. Teaching students basics of immunogenetics.
3. Explaining HLA typization.
4. Introducing basic Blood tests.
5. Providing basic concepts of immune system
6. Explaining basic concepts in autoimmunity

COURSE CONTENT
Week
Topic
  1. Introduction to immunology
  2. Properties and overview of immune responses. y TEST 1 (5 points) Antibodies and antigens. Major histocompatibility complex molecules
  3. Cells and tissues of immune system Innate immunit
  4. Workshop 1
  5. Antibodies and antigens
  6. MHC and antigen presentation to T Lymphocytes
  7. Immune receptors and signal transduction
  8. MID-TERM EXAM WEEK
  9. Lymphocyte development and antigen receptor rearangement
  10. Workshop 2
  11. Activation of T lymphocytes
  12. B cell activation and antibody production. Immunological tolerance. Cytokines
  13. Effector mechanisms of cell-mediated and humoral immunity
  14. Immunity to microbes, Transplantation immunology, Autoimmunity
  15. Immunity to tumors, Hypersensitivity

LABORATORY/PRACTICE PLAN
Week
Topic
  1. Beginning of classes
  2. Introduction to lab course
  3. Blood Smear
  4. Leukocyte count
  5. RBC count

  1. Determination of blood groups
  2. Separation of blood components, bleeding time bleeding and clotting time, interpretation of blood test resultsBlood Groups
  3. MID-TERM EXAM
  4. Precipitation of blood proteins
  5. Dilution techniques and basic calculations needed in immunology lab
  6. Leukocyte isolation
  7. ELISA
  8. Lab Make-up
  9. Preparation for practical exam
  10. Practical Exam

TEACHING/ASSESSMENT
Description
  • Interactive Lectures
  • Practical Sessions
  • Excersises
  • Presentation
  • Discussions and group work
  • Problem solving
  • Assignments
  • Case Studies
Description (%)
Method Quantity Percentage (%)
Quiz210
Midterm Exam(s)120
Presentation110
Laboratory120
Final Exam140
Total: 100
Learning outcomes
  • Describe basic organs of the limmune system
  • Comprehend the basics of cellular immunity
  • Comprehend the basics of humoral immunity
  • Perform immunological detection of viruses and bacteria
  • Understand the fundamentals of immunological laboratory procedures
  • Interpret immunological laboratory results
  • Perform ABO, MN, Rh blood typing
  • Understand the molecular basis of immunity
TEXTBOOK(S)
  • Abbas, A. K., Lichtman, A. H. H., & Pillai, S. (2011). Cellular and molecular immunology, 7th ed. Philadelphia, PA, USA:
  • Saunders

ECTS (Allocated based on student) WORKLOAD
Activities Quantity Duration (Hour) Total Work Load
Lecture (14 weeks x Lecture hours per week)15230
Laboratory / Practice (14 weeks x Laboratory/Practice hours per week)15230
Midterm Examination (1 week)122
Final Examination(1 week)122
Preparation for Midterm Examination11414
Preparation for Final Examination11515
Assignment / Homework/ Project11414
Seminar / Presentation11818
Total Workload: 125
ECTS Credit (Total workload/25): 5