INTERNATIONAL BURCH UNIVERSITY
Faculty of Engineering and Natural Sciences
Department of Genetics and Bioengineering
2015-2016

SYLLABUS
Code Name Level Year Semester
GBE 338 Immunology and Immunogenetics Undergraduate 3 Spring
Status Number of ECTS Credits Class Hours Per Week Total Hours Per Semester Language
Area Elective 5 2 + 2 125 English

Instructor Assistant Coordinator
Mirsada Hukić, Prof. Dr. Mirsada Hukić, Prof. Dr. Mirsada Hukić, Prof. Dr.
[email protected] [email protected] no email

This course provides a broad survey of modern immunology, covering such topics as molecular concepts of antigenic specificity,chemistry of antibodies and their interactions with antigens and cells, regulation of the immune response,transplantation,autoimmunity, and tumor immunology. The course is taken concurrently with a lab course, which is teaching students basic experimental concepts in immunology, such as differential blood picture, counting blood cells, HLA typing, and hemoglobin analysis.

COURSE OBJECTIVE
Providing a theoretical and applied perspective of classical and modern immunology.
Teaching students basics of immunogenetics.
Explaining HLA typization.
Introducing basic Blood tests.
Providing basic concepts of allergy.
Explaining autoimmunity.

COURSE CONTENT
Week
Topic
  1. Properties and overview of immune responses. Innate immunity
  2. Cells and tissues of immune system
  3. Antibodies and antigens. Major histocompatibility complex molecules
  4. Antigen processing and presentation to T lymphocytes. Antigen receptors and accessory molecules of T lymphocytes
  5. Lymphocyte development and antigen receptor gene rearrangement
  6. Activation of T lymphocytes
  7. B cell activation and antibody production
  8. MID-TERM EXAM WEEK
  9. Immunological tolerance. Cytokines
  10. Effector mechanisms of cell-mediated and humoral immunity
  11. Immunity to microbes
  12. Transplantation immunology
  13. Autoimmunity
  14. Immunity to tumors
  15. Hypersensitivity

LABORATORY/PRACTICE PLAN
Week
Topic
  1. Beginning of classes
  2. Introduction to lab course
  3. Blood smear preparation
  4. Differential leukocyte counting
  5. Counting erythrocytes using Neubauer chamber
  6. Counting leukocytes using Neubauer chamber

  1. Counting thrombocytes
  2. MID-TERM EXAM
  3. Determination of blood groups and coagulation time
  4. Separation of Plasma and Serum and Differences between Plasma and Serum
  5. Precipitation of proteins from blood serum and plasma
  6. Urine Analysis
  7. Diagnosis of disease based on immune response—a virtual laboratory exercise
  8. Preparation for practical exam
  9. Practical Exam

TEACHING/ASSESSMENT
Description
  • Interactive Lectures
  • Practical Sessions
  • Presentation
  • Discussions and group work
Description (%)
Method Quantity Percentage (%)
Midterm Exam(s)120
Laboratory120
Class Deliverables120
Final Exam140
Total: 100
Learning outcomes
  • Prepare and interpret blood smears
  • Describe basic organs of the lymph system
  • Perform ABO, MN, Rh blood typing
  • Isolate blood proteins
  • Interpret blood lab results
  • Perform immunological detection of viruses and bacteria
TEXTBOOK(S)
  • Abbas, A. K., Lichtman, A. H. H., & Pillai, S. (2011). Cellular and molecular immunology, 7th ed. Philadelphia, PA, USA:
  • Saunders

ECTS (Allocated based on student) WORKLOAD
Activities Quantity Duration (Hour) Total Work Load
Lecture (14 weeks x Lecture hours per week)15230
Laboratory / Practice (14 weeks x Laboratory/Practice hours per week)15230
Midterm Examination (1 week)122
Final Examination(1 week)122
Preparation for Midterm Examination11414
Preparation for Final Examination11515
Assignment / Homework/ Project11414
Seminar / Presentation11818
Total Workload: 125
ECTS Credit (Total workload/25): 5