INTERNATIONAL BURCH UNIVERSITY
Faculty of Engineering and Natural Sciences
Department of Genetics and Bioengineering
2016-2017

SYLLABUS
Code Name Level Year Semester
GBE 210 Biochemistry Undergraduate 2 Spring
Status Number of ECTS Credits Class Hours Per Week Total Hours Per Semester Language
Compulsory 6 3 + 2 149 English

Instructor Assistant Coordinator
Monia Avdić - Ibrišimović, Assist. Prof. Dr. Monia Avdić Ibrišimović Monia Avdić - Ibrišimović, Assist. Prof. Dr.
[email protected] [email protected] no email

This course provides a broad survey of biochemistry from the molecular aspects. It covers the major chemical and biological foundations of biochemistry. The first section of the course focuses on topics related to carbohydrates, proteins, lipids and nucleic acids. Special emphasis is given to the processes of protein synthesis and gene expression. The second part of the course focuses on the metabolism of carbohydrates, lipids and nitrogen. All these cycles are analyzed through a medical and molecular perspective.

COURSE OBJECTIVE
TThe cognitive, affective and behavioral objectives of this course are following:
Providing a theoretical and applied knowledge in the field of biochemistry
Comprehending the molecular components of the cell
Understanding the metabolism of carbohydrates
Understanding the metabolism of lipids
Understanding the metabolism of nitrogen
Learning normal biochemical test results
Interpreting abnormal results
Learning to do and interpret biochemical laboratory tests

COURSE CONTENT
Week
Topic
  1. Introduction to Biochemistry
  2. Molecular Components of the Cell
  3. An overview of fuel metabolism
  4. Water, Acids, Bases and Buffers; Structure of the Major comnpounds of the body
  5. Amino Acids and Proteins; Structure- Function relationship in proteins
  6. Enzymes as catalysts; Regulation of Enzymes
  7. Nucleic Acids, Synthesis of DNA, Transcription
  8. Mid-term exam
  9. Translation, regulation of gene expression
  10. Cellular Energetics, TCA
  11. Oxidative Phosphorilation, Glycolysis, Oxidation of Fatty Acids and Ketone bodies
  12. Carbohydrate Metabolism
  13. Carbohydrate Metabolism
  14. Lipid Metabolism
  15. Nitrogen Metabolism

LABORATORY/PRACTICE PLAN
Week
Topic
  1. Beginning of classes
  2. Basic calculations
  3. Solution preparation, buffers
  4. Quantitative estimation of amino acids by ninhydrin

  1. Separation of amino acids by TLC
  2. Titration curves of amino acids
  3. Isoelectric precipitation of proteins
  4. Mid-term exam
  5. Effect of temperature on enzyme kinetics
  6. Effect of enzyme concentration on enzyme kinetics
  7. Effect of substrate concentration on enzyme kinetics
  8. Qualitative analysis of carbohydrates
  9. Estimation of saponification value of fats and oils
  10. Preparation for practical exam
  11. Practical exam from lab course

TEACHING/ASSESSMENT
Description
  • Interactive Lectures
  • Practical Sessions
  • Excersises
  • Presentation
  • Discussions and group work
  • Student debates
  • Problem solving
  • Assignments
  • Case Studies
Description (%)
Method Quantity Percentage (%)
Quiz126
Homework24
Midterm Exam(s)120
Presentation110
Laboratory15
Lab/Practical Exam(s)115
Term Paper15
Final Exam135
Total: 100
Learning outcomes
  • Understand the significance of the water molecule and its properties that are essential to sustain life
  • Comprehend the structure and function of amino-acids and proteins
  • Categorize enzymes and determine enzyme activity
  • Comprehend the basics of carbohydrates and their metabolsim
  • Comprehend the basics of lipids and their metabolsim
TEXTBOOK(S)
  • 1. Lieberman, M., Marks, A. D., Smith, C. M., & Marks, D. B. (2007). Marks\' essential medical biochemistry. Lippincott Williams & Wilkins.

ECTS (Allocated based on student) WORKLOAD
Activities Quantity Duration (Hour) Total Work Load
Lecture (14 weeks x Lecture hours per week)15345
Laboratory / Practice (14 weeks x Laboratory/Practice hours per week)15230
Midterm Examination (1 week)122
Final Examination(1 week)122
Preparation for Midterm Examination11515
Preparation for Final Examination11515
Assignment / Homework/ Project12020
Seminar / Presentation12020
Total Workload: 149
ECTS Credit (Total workload/25): 6