INTERNATIONAL BURCH UNIVERSITY
Faculty of Engineering and Natural Sciences
Department of Genetics and Bioengineering
2015-2016

SYLLABUS
Code Name Level Year Semester
GBE 102 Cell Biology Undergraduate 1 Spring
Status Number of ECTS Credits Class Hours Per Week Total Hours Per Semester Language
Compulsory 5 2 + 2 127 English

Instructor Assistant Coordinator
Lada Lukić-Bilela, Assist. Prof. Dr. Sanida Buljubasic Lejla Smajlović Skenderagić, Assist. Prof. Dr.
[email protected] [email protected] no email

The lectures of this course are devoted to structural details and the molecular functions of the various components of the cell. Lectures will introduce topics such as endocytosis, intra-membrane transport, protein targeting, organelle biosynthesis, protein sorting, exocytosis, cell shape, motility and cell-to-cell interaction. Lectures will also focus on signal transduction, processes and cellular functions that are required for cell growth and programmed cell death (apoptosis). Upon completion of the course, students should have a comprehensive understanding of the architecture and function of living cells. This course is taken concurrently with a laboratory course.

COURSE OBJECTIVE
Making a detailed study on chemical components of cells.
Introduction to the basics of energy, catalysis, and biosynthesis.
Illustrating the structure and function of the plasma membrane and cytoskeleton.
Explaining the structure and function of mitochondrion and chloroplast.
Studying proteins and DNA.
Teaching the cell's interaction with its environment and cytoplasmic membrane systems.
Illustrating basic microscopy of different cell types.

COURSE CONTENT
Week
Topic
  1. Introduction to cells: The discovery of cells, basic properties of cells, prokaryotes and eukaryotes
  2. Cell chemistry
  3. Energy, catalysis, and biosynthesis
  4. Structure and function of the plasma membrane
  5. Membrane transport
  6. How cells obtain energy from food
  7. Intracellular compartments and transport
  8. MID-TERM EXAM WEEK
  9. Cytoskeleton. Cell communication
  10. Cell division
  11. Cell cycle control, and cell death
  12. The extracellular space
  13. Cell differentiation
  14. DNA and chromosomes
  15. Protein structure and function

LABORATORY/PRACTICE PLAN
Week
Topic
  1. Beginning of classes
  2. Introduction, lab safety
  3. Introduction to Microscopy; Observation of cells
  4. Osmosis and Diffusion
  5. Spectrophotometric analysis of membrane stability in beet root cells

  1. Cellular fractionation
  2. Isolation and counting of chloroplast
  3. MID-TERM EXAM WEEK
  4. Isolation and determination of enzyme concentration
  5. Analysis of polysaccharides
  6. Mitosis
  7. Barr body observation
  8. Karyotyping
  9. Preparation for practical exam
  10. Practical Exam

TEACHING/ASSESSMENT
Description
  • Interactive Lectures
  • Practical Sessions
  • Presentation
  • Discussions and group work
Description (%)
Method Quantity Percentage (%)
Midterm Exam(s)120
Laboratory120
Class Deliverables120
Final Exam140
Total: 100
Learning outcomes
  • Show the basic structure of the cell
  • Recognize molecular mechanisms in the cell
  • Interpret cell metabolism
  • Memorize cell cycle, mitosis and meiosis
  • Identify distinction between prokaryotic and eukaryotic cells
  • Illustrate the structure of plant cells in leaf, stem and root
  • Explain the structure of animal cells through the study of human blood cells
  • Describe basic cytogenetics and human karyotype
TEXTBOOK(S)
  • Alberts, B., Bray, D., Hopkin, K., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P. (2014). Essential Cell
  • Biology, 5th ed. New York, NY, USA: Garland Science

ECTS (Allocated based on student) WORKLOAD
Activities Quantity Duration (Hour) Total Work Load
Lecture (14 weeks x Lecture hours per week)15230
Laboratory / Practice (14 weeks x Laboratory/Practice hours per week)15230
Midterm Examination (1 week)122
Final Examination(1 week)122
Preparation for Midterm Examination11212
Preparation for Final Examination11515
Assignment / Homework/ Project11818
Seminar / Presentation11818
Total Workload: 127
ECTS Credit (Total workload/25): 5